Arsenal midfielder Aaron Ramsey left out of Wales squad

Wales manager Chris Coleman has revealed he will be without Arsenal’s Aaron Ramsey for the Dragons’ upcoming World Cup qualifier against Moldova.

The midfielder suffered a hamstring injury in the Gunners’ Premier League opener against Liverpool, and Gunners boss

Arsene Wenger said he would not be fit until after the international break

Coleman on Wednesday named his squad for the Moldova game in Cardiff on September 5, and said he expected Ramsey to be out for another three weeks.

“When you’ve got a player as good as Aaron, take him out of any team and you are going to know about it,” said the Wales boss.

“He is irreplaceable, he makes a huge impact for us. He is a great player and it’s a shame he’s not here. He’s a loss to any team.”

Wales show three changes to the squad which reached the semi-finals of Euro 2016 this summer.

Jonathan Williams is expected to be out for a couple of months after suffering an ankle injury in a Crystal Palace pre-season friendly, while veteran Nottingham Forest midfielder David Vaughan has announced his retirement from international football .

“Jonny has had a good impact on the team and brings something different,” said Coleman.

“I saw that tackle on him, it was a coward’s tackle from behind, and that was annoying.

“Vaughny sat down with me when he got back from France and explained he was going to retire.

“I tried to talk him out of because he’s been with us for so long and he’s got good quality.

“But he wants to spend more time with his family and concentrate on his club career, and we’ve got to respect that.

“He’s been a great servant for Wales.”

Wales squad for the World Cup qualifier against Moldova in Cardiff on September 5:

Hennessey (Crystal Palace), Ward (Liverpool), O Fon Williams (Inverness); Gunter (Reading), Chester ( Aston Villa ), A Williams (Everton), Collins (West Ham), Davies (Tottenham), Richards (Cardiff), Taylor (Swansea), Dummett (Newcastle); Allen (Stoke), Ledley (Crystal Palace), Huws (Cardiff), King (Leicester), Edwards (Wolves), G Williams (Fulham), Cotterill (Birmingham); Bale (Real Madrid), Robson-Kanu (unattached), Vokes ( Burnley ), Church ( MK Dons), Lawrence (Leicester).